In this work, results of two software’s are presented. A first software, that simulates the three-dimensional geometry of an aircraft passenger cabin section, generate the occupants and interior and surroundings surfaces, and a second software, that simulates the passenger’s thermal response, evaluates the level of thermal comfort that the passengers are subjected. The aircraft passenger cabin section consists of five rows, upper ventilation system and luggage compartment, floor and roof and is occupied by thirty passengers. Each row is made up of six benches: three on the left and three on the right side. In this work, the design of the aircraft passenger cabin section and hydrothermal manikins are presented and the level of comfort, which passengers are subject, is calculated. According to the results obtained, in general, taking into account the input data, the level of thermal comfort is acceptable according to category b of the international standards.