错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

Peptides as Alternatives to Antibiotics in Poultry Health Management

  • Inkar Castellanos-Huerta,
  • Abdiel Atencio Vega,
  • Jesus A. Maguey-Gonzalez,
  • Lauren Laverty,
  • Awad A. Shehata,
  • Wolfgang Eisenreich,
  • Billy M. Hargis,
  • Guillermo Tellez-Isaias

摘要

The poultry industry faces a critical challenge: antibiotic resistance. Once considered miraculous, antibiotics now breed resilient pathogens, endangering poultry health and global food security. Widespread antibiotic use has created resistant strains, threatening poultry and public health. Peptides, with diverse structures and functions, emerge as promising alternatives for sustainable poultry health. These small yet potent molecules offer a unique approach to disease control, targeting a broad spectrum of pathogens. As short amino acid chains, Peptides possess distinctive properties crucial for combating infectious agents. Antimicrobial Peptides (AMPs) play a central role in defense mechanisms, disrupting microbial membranes. The transition to peptides signifies a paradigm shift in disease control, addressing threats from Salmonella, Escherichia coli, and viruses. Peptides exhibit multifaceted functionalities, tackling resistance concerns and preventing future strains. Peptides offer hope in crisis, with antimicrobial, immunomodulatory, and wound-healing capabilities. Their comprehensive approach uniquely targets invaders, disrupting membranes, inhibiting processes, and orchestrating immune responses. This exploration unveils the potential of peptides in mitigating threats from antibiotic-resistant pathogens. Peptides as antibiotic alternatives promise effective and sustainable poultry health management, marking a crucial step toward resilient farming practices.