This chapter uses concepts from critical interculturality to explore interprofessionality. The main argument is that interprofessionality can be studied as the negotiation of professional identities (similarities and differences among representatives of different occupations) to establish a shared and just working culture geared towards the provision of quality care. Interprofessional team culture is thus understood as a communicative process where a small group of people construct their “small culture”—shared meanings and rules of engagement—as they interact with one another on a daily basis. This stands in contrast to an essentialist view of culture, which sees culture as composed of a priori identity categories, such as “nurse.” However, some characteristics of the healthcare context, such as the need for plug-and-play teaming and for fast action in emergency situations, may mean that negotiations of interprofessionality are not always the most productive nor the safest way of organizing work; there are times when care providers need to fall back on essentialist notions of professional identities. The concept of simplexity is proposed to describe how interprofessional team members orient themselves to others in interaction as continuously moving along a continuum, with simplistic essentialist understandings about identity at one end and appreciation for identities as complex, multifaceted, and dynamic at the other.