This volume is the fourth in a series of books on Digital Sovereignty in economy. In this volume, Digital Sovereignty of companies and other organizations is the focus. Digital Sovereignty at the organizational level is described through the concepts of human, structural, and relational capital, which represent key elements of an organization’s capacity to address (digital) challenges. Human capital refers to the knowledge and competences of the individual employees within the company. The structures and processes enabling the organization to access, combine, and develop its knowledge base constitute structural capital. Relational capital relates to knowledge available through the external relations of the organization. These three types of capital are integrated with two key aspects of control to form a core pillar of sovereignty: confidence in action—the degree to which an organization can trust that the selected actions will achieve the intended results—and freedom of action—the variety of options available for the organization to pursue its aims. The three kinds of capital combined with the two aspects of control yield a matrix with six cells, which can be used to analyze and design digital sovereignty for organizations. In this book, contributions from computer science, economics, social sciences, organizational psychology, work psychology and human factors, mechanical and industrial engineering, and law describe interdisciplinary building blocks for Digital Sovereignty. These contributions are presented with respect to the six cells of the analysis and design matrix, highlighting their relevance for individual aspects of Digital Sovereignty.