Myasthenia Gravis

Myasthenia gravis (MG) is an autoimmune disease that affects the post-synaptic area of the neuromuscular junction. Its hallmark is the weakness that worsens with activity. The incidence of MG has been increasing in recent decades ranging from 4.1 to 30 cases per million person-years, which is considered to be due to the aging population or unknown environmental factors. The disease has several subtypes that differ slightly in their clinical characteristics, immunological markers, population distribution, and suitable treatments. The autoimmune nature of the disease is manifested by a decrease in the number of acetylcholine receptors in the muscle receptors, which makes the endplate potential lower than the threshold needed to activate muscle fiber action potential. Herein, we present a review of MG concentrating on the diagnosis.