Influence of Disease on Drug Interaction

As the aging population increases, the prevalence of patients living with multiple chronic conditions (MCCs) has also risen. This presents a challenge in medication management, as prescribing practices often focus on individual disease-based indications, resulting in a heightened risk of adverse drug events (ADEs) in MCC patients. This risk is exacerbated by factors such as polypharmacy, over-the-counter medications, herbal supplements and drug-disease interactions that can interfere with the patient’s current drug regimen. To mitigate the occurrence of ADEs in patients with MCCs, it is essential to optimize drug therapy through careful consideration of medication appropriateness and potential interactions.