Currently, geopolymers are introduced as sustainable construction materials with high durability performance and lower carbon dioxide emission. This experimental work prepared geopolymer concrete specimens with 30, 40, 50, 60, and 70% of tile ceramic waste powder (TCWPs) as ground blast furnace slag (GBFS) replacement. Then, the natural coarse and fine aggregates, including crushed stone and river sand, were replaced by 10, 20, and 30 vol% of discarded rubber tire crumbs (DRTCs). The effect of TCWPs and DRTCs inclusion on the geopolymer matrix workability, compressive strength, and splitting tensile and flexural strengths are assessed. From the results obtained, it was found that the content of TCWPs and DRTCs significantly influences the proposed geopolymer’s workability. The results show the increasing content of TCWPs as GBFS replacement led to improved concrete workability. However, the utilization of DRTCs as natural aggregate replacements negatively affects slump value and workability, with a trend to decrease with increasing replacement levels. Moreover, the results show an inverse relationship between TCWPs and DRTCs content and strength development of proposed concrete. The loss in strength was found to increase with increasing content of both TCWPs and DRTCs. However, the investigated geopolymer concrete achieved acceptable compressive strength (more than 25 MPa), which can be considered for many applications in construction sectors. It is shown that using TCWPs and DRTCs in geopolymer production can help produce construction materials with reduced environmental impacts, including carbon emissions and landfill problems.