Hybridization from the Earliest Times till Darwin

Questions regarding the transmission of characteristics from parents to offspring have been asked since very early times. Around 420 BC, HippocratesHippocrates proposed the idea of pangenesispangenesisin Hippocrates' work, whereby body parts contributed their characteristics to the gametes. Camerarius first demonstrated sexuality in plants in 1694, while Kölreuter later obtained the first hybrids experimentally, and Knight was the first to observe segregationsegregation. In 1862, NaudinNaudin, Charles proposed that a hybrid consisted of two specific essencespecific essencesspecific essence that were separated in the pollen and ovule. Unaware of Mendel’sMendel, Gregor Johann work, DarwinDarwin, Charles Robert proposed the provisional hypothesis of pangenesispangenesisDarwin's provisional hypothesis of (1868) in 1868.