Researchers are increasingly asking questions about the complex ways in which digital media transects family life for the purpose of understanding health and development. Most research in this domain is informed by theoretical models that champion the primacy of individuals (i.e., the child). However, family systems theory (FST) has long emphasized that the family unit itself, versus the child, should be the focus of study, assessment, and intervention. This paradigm remains underutilized in research related to digital media and health. The present chapter provides a primer in FST for researchers and clinicians who are interested in media. Core concepts such as holism, organization, feedback, and resilience are reviewed. These principles are contrasted with individual-focused theoretical models. The digital level of analysis is outlined as a conceptual frame of reference and ecological layer of organization that can be applied in future digital media studies. Lastly, recommendations for research, practice, and policy are provided, with an emphasis on responsible digital innovation and application of new technologies.