In recent years, societal narratives around teens and screens have shifted significantly. First, high-profile media coverage has raised concerns over the negative impact of technology use on the mental health, well-being, and physical safety of adolescents. Consequently, this has led to restrictive approaches to implementing parental control software, age verification systems, artificial intelligence-based risk detection, and other safety mechanisms to protect teens from such harm. At the same time, recommendations regarding digital technology use have moved beyond imposing time limits to more advanced frameworks that consider active and intentional technology use. Additionally, research recommends shifting from restrictive parenting practices to include more developmentally appropriate and resilience-based approaches that empower teens as they prepare for adulthood. Yet, researchers have acknowledged that solutions towards digital inclusion cannot be “one-size-fits-all,” as individual development, family differences, and cultural norms may influence youth outcomes. Finally, we have seen more tangible efforts through human-centered design and legislative policies targeted toward making digital platforms that engage teen users more accountable for their online safety. In this chapter, we discuss these trends and raise important questions and recommendations for setting a forward-thinking agenda for future socio-technical research and practice on promoting the digital well-being and safety of teens.