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Genomic sequences have a significant proportion of repetitive DNA nucleotides. The repetitive regions are functionally important and can be broadly classified as tandem repeats (TRs) and dispersed repeats. Computational methods have been used to identify the presence of these regions. Signal Processing (SP) based computational methods require the mapping of DNA sequences into numeric ones. Large numbers of mapping schemes have been reported for this purpose. The mapping strategy employed affects the sensitivity and specificity of the SP-based algorithms. In this work performance of Ramanujan Fourier transform based TR detection algorithm with different mapping schemes has been studied. Complex mapping scheme has been identified as the best mapping scheme for the TR detection.

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Evaluation of Different Mapping Schemes for Detection of Tandem Repeats in DNA Sequences

  • 会议论文

  • 发表日期：

    2025年

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  • Yashpal Yadav,
  • Sanjeev Narayan Sharma,
  • Devendra Kumar Shakya

摘要

Genomic sequences have a significant proportion of repetitive DNA nucleotides. The repetitive regions are functionally important and can be broadly classified as tandem repeats (TRs) and dispersed repeats. Computational methods have been used to identify the presence of these regions. Signal Processing (SP) based computational methods require the mapping of DNA sequences into numeric ones. Large numbers of mapping schemes have been reported for this purpose. The mapping strategy employed affects the sensitivity and specificity of the SP-based algorithms. In this work performance of Ramanujan Fourier transform based TR detection algorithm with different mapping schemes has been studied. Complex mapping scheme has been identified as the best mapping scheme for the TR detection.