Optical Coherence Tomography in Dermatology

Non-invasive imagingNon-invasive imaging techniques opened new horizons in the dermatological daily practice. Besides reflectance confocal microscopyReflectance confocal microscopy, optical coherence tomographyOptical coherence tomography (OCT) and line-field confocal OCT haveLine-field-confocal optical coherence tomography been used in the diagnosis, grading and follow-up of non-melanoma skin cancersSkin cancer" and other non-neoplastic dermatological conditions such as mite infections and inflammatory skin diseasesinflammatory skin diseases.Inflammatory skin diseasesOCT and dynamic OCTDynamic optical coherence tomography reach the deeper dermis and provide an overview of the blood vessel morphology and density, allowing semi-automated objective measurements of blood flow but also of skin thickness, roughness, and the attenuation coefficient. LC-OCT can count on lower penetration depth than OCT but higher resolution and can therefore be compared intuitively with histology. Both devices can potentially be used in artificial intelligenceArtificial intelligence guided diagnostic studies.