Psychobiotics: A Restorative Intervention for Lifestyle-Induced Deteriorations of Mental Health

Sound mental healthMental health is increasingly recognized as a crucial necessity for the overall well-being, particularly in ageingAgeing populations. Numerous studies have highlighted that exposure to and subsequent infestations of pollutants, high-fat/high-sugar diets, alcohol, sedentary lifestyles, and lack of exercise have immense disastrous effects on mental healthMental health. In addition, internal mechanisms such as proteostasisProteostasis imbalance contribute in a major way to a decline in mental healthMental health. In addition, a key cause of disrupted brain function is an outcome of altered gut microbiotaGut microbiota, leading to dysbiosis, and which relies on external and internal agents to maintain their integrity. Interestingly, psychobioticsPsychobiotics, a subset of probiotics, specifically modulate the functions of the central nervous system, in corcordance with the immune, humoral, neural and metabolic networks, to enhance antidepressant and anxiolytic effects. Thus, a comprehensive understanding of the psychobioticsPsychobiotics, and defining the causative factors influencing mental healthMental health which may be ameliorated by psychobioticsPsychobiotics, will aid in developing effective psychotherapeutic treatment strategies in the near future.