MR-LINAC Radiotherapy for CNS Tumors
摘要
Magnetic resonance image-guided radiotherapy (MRIgRT) permits daily anatomical and functional imaging, made possible with the recent clinical availability of two hybrid MR-LINAC (MRL) systems. Anatomical tumor changes, particularly in glioblastoma, motivate more regular monitoring of tumors during a course of RT, which can only be done with MRI. Intelligent, functionally derived, and personalized RT treatment volumes instead of a geometric expansion on gross tumor, including a boost to a treatment-resistant subvolume, can now be clinically tested using an MRL. This chapter discusses the motivation and technical application of MRL for CNS malignancies.