Adult Intracranial Ependymoma

Ependymomas are uncommon tumors arising from the ependymal cells lining the ventricles, central canal, filum terminale, or choroid plexus. Clinical presentation depends on the tumor location. Prognostic factors include extent of resection, tumor grade, age at time of diagnosis, performance status, tumor location, and possibly receipt of adjuvant radiation therapy, with arguably extent of resection being the most significant factor. The predominant pattern of recurrence is local recurrence. Management of adult intracranial ependymoma remains controversial, and multi-institutional prospective trials are needed.