Comparison of Eye-Tracking Parameters and Brain Oxygen Saturation in Patients with COVID-19 Moderate Pneumonia

The aim was to study the relationship between eye tracking (ET) parameters and cerebral tissue oxygen saturation (SctO2) values in the acute period of moderate COVID-19 pneumonia. Materials and Methods. A single-centre, non-randomised study included 92 patients in the acute period of SARS-CoV-2 moderate pneumonia (Delta variant). The mean time from admission was 1.5 ± 0.9 days. M:49, W:43. The mean age was 34.7 ± 3.9 years. The eye vergence reactivity index (VRx) was determined using a mobile ET. The cerebral oximetry was performed using Fore-Sight 2030 and included the detection of the SctO2 level in the frontal lobe (FLP) region. Statistical analysis was carried out using the methods of parametric statistics. Results. The calculated vertical VRx was 0.781 ± 0.118. The calculated horizontal VRx was 0.821 ± 0.107. SctO2 in the FLP varied within the range from 61% to 73%. The average SctO2 values were 65.4 ± 5.2% over the left FLP and 66.2 ± 6.3% over the right FLP (p = 0.872). The regression analysis showed that HVRx and VVRx were correlated with SctO2 levels in both FLPs (p = 0.035 and p = 0.034, respectively, and p = 0.040 and p = 0.049, respectively). Conclusions. Cerebral oxygen saturation in moderate pneumonia caused by the SARS-CoV-2 coronavirus has a significant destabilising effect on the oculomotor synergy (VVRx and HVRx) (p < 0.05).