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Silicon Nitride for Total Hip Arthroplasty

  • Kengo Yamamoto,
  • Yasuhito Takahashi,
  • Toshiyuki Tateiwa,
  • Makiko Yorifuji,
  • Bryan J. McEntire,
  • Giuseppe Pezzotti

摘要

Total hip replacement (THR) has become a remarkably successful surgical procedure, offering significant pain relief and restoration of a functional and productive lifestyle for millions of patients worldwide suffering from hip diseases and disorders. Over the past five decades, continuous advancements in surgical techniques and prosthetic implants have been directed towards minimizing the need for revision surgery and ensuring the longevity of the implants throughout a patient’s natural lifespan. While advancements in biomaterials, surgical techniques, and rehabilitation protocols have demonstrably improved patient outcomes through more durable materials, faster recovery, and enhanced mobility, the predicted lifetime of total hip arthroplasty (THA) components remains largely unchanged at approximately 20 years. Despite ongoing research and progress, the predominant failure modes haven’t shown significant improvements. Introducing silicon nitride as a femoral head material in hard-on-soft bearing articulations presents a potential breakthrough in extending implant longevity, possibly achieving or surpassing a patient’s natural lifespan. Silicon nitride offers several potential advantages for younger active patients undergoing hip replacement. First, silicon nitride exhibits wear performance against modern polyethylene that is competitive with, or even exceeds, the best currently available femoral head technologies. Second, unlike oxide ceramics that release oxygen and contribute to polyethylene degradation, silicon nitride, a non-oxide ceramic, removes oxygen from the tribolayer, potentially mitigating this issue. Third, it demonstrably reduces fretting crevice corrosion at modular junctions compared to metal femoral heads. Finally, silicon nitride boasts superior fracture strength and toughness when compared to most other bioceramics. These combined benefits strongly support further investigation of silicon nitride femoral heads. Ideally, well-designed clinical trials will confirm the promising results observed in pre-clinical testing.