Designing an Electronic Circuit to Emulate the Control of Pharmacological Processes

Recent technological advances in the context of medical cyber-physical systems (MCPS) have enabled the development of the personalization of medical decisions according to the specific needs of the patient applied, for instance, on the optimization of absorption of drugs (pharmacological processes). One of the emerging research themes in this area is the adaptation of drug delivery based on the specific characteristics of the patient, a problem that could be solved by designing gain-scheduled controllers in terms of the variation of parameters measured in real-time, such as concentration of certain chemical components in the blood, liver, kidneys, etc., and subsequent supply adequate compensation for the use of, for example, infusion pumps. In that regard, based on a state-space mathematical model of a discrete-time linear MCPS, this paper proposes the design of an electronic circuit that emulates a patient’s reaction to a certain pharmacological process. It is intended to perform circuit stability analysis tests so that in future projects it can be connected to a programmable logic controller (CLP), or microcontroller allowing testing of the effectiveness of controllers that guarantee a proper administration of drugs in the body.