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Nanoparticles as Immunomodulators

  • Nagasai C. Adusumilli,
  • Adam J. Friedman

摘要

Formulating active ingredients through nanoparticles is increasingly showing promise for a wide range of dermatologic indications. As the mechanistic understanding of nanoparticle interaction with skin strata continues to develop, this strategy of drug formulation and delivery has diverse implications for cutaneous immunomodulationImmunomodulation. NanomedicineNanomedicine may allow localized, topical delivery of both established immunomodulatorsImmunomodulators and novel compounds with anti-inflammatoryAnti-inflammatory properties. This brief chapter outlines the principles of nanoformulation for the skin, summarizes the latest evidence for nanoparticles as immunomodulators in dermatologyDermatology, and discusses future directions for this quickly advancing therapeutic field.