In the field of medicine, quality of patient care and preservation of patient health are paramount. As such, new technologies and techniques are constantly being developed and improved upon to better optimize patient responses to therapies and interventions. One of the major emergent domains of modern medical research deals with digital biomarkersDigital biomarkers and their application in clinical and nonclinical settings. From established techniques involving routine laboratory testing to the introduction of wearable smart devices and microtechnologies, digital biomarker collection and analysis aims to revolutionize medical practice and research studies. In the field of dermatology, such biomarkers may allow physicians and researchers to better manage acute and chronic inflammatory conditions, cut down time-to-recognition of cancers and other time-sensitive conditions, increase compliance to medication use, optimize research design, and improve overall patient health.