Skeletal Dysplasias

The skeletal dysplasias (or more appropriately, the osteochondrodysplasias) are genetic disorders that affect the development of the skeletal and cartilaginous tissues. They are of interest to pediatric endocrinologists not only because most have an impact on linear growth causing short stature but also because of what these disorders teach us about the mechanisms and regulation of growth. Current and emerging treatments for specific syndromes are often managed by pediatric endocrinology.