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Probiotic Therapies for Skeleton and Bone Health

  • Birbal Singh,
  • Gorakh Mal,
  • Rajkumar Singh Kalra,
  • Francesco Marotta

摘要

The bones and skeleton are very important supportive parts of the body which protect vital organs from injury. In addition, the bones stock minerals such as calcium and phosphorous and release them when needed for physiological activities. Intestinal microorganisms and their metabolites influence and act as key regulators of bone health, postnatal skeletal development, and involution. As gut microorganisms interact with all organs including the bones, brain, liver, and other, the use of probiotics to manipulate GI microorganisms to augment endoskeleton health via gut-brain-bone-axis is an interesting area of microbial therapies.