Synthetic Microbes to Modulate the Gut Ecosystem
摘要
Probiotic or human microbiota are multipurpose microbial therapeutics to treat metabolic disorders and infectious and noninfectious diseases. As diagnostic tools, the engineered microorganisms have emerged as “smart” supportive therapies to diagnose and cure health problems. Challenges, such as biocontainment and risk of transmission of recombinant genes to other microorganisms, associated with the use of synthetic or engineered probiotics have to be ascertained.