Novel Insights into the Human Microbiome and Its Functions
摘要
Over the past years, biological sciences have transformed strongly and shaped our understanding about the composition and role of the human microbiome in health and disease. Culture-independent technologies have unraveled the community structure and amazing role of the human microbiome. New generation sequencing technologies, synthetic biology, artificial intelligence, gene-editingGene-editing, and in silico analysis of massive data have provided novel information on the role of the human microbiome in nutrition, health and behavior, development and immunity, and connection with noncommunicable diseases. System-level understanding is essential to evolve strategies to benefit humans from the genetic and metabolic repertoire of the human microbiome. New insights might translate the available microbiological information into diagnostic, therapeutic, and preventive developments in the context of personalized precision medicine.