Malignant skin infiltration can occur in any lymphoid neoplasm. Chronic lymphocytic leukemia (CLL), T-cell prolymphocytic leukemia (T-PLL), adult T-cell leukemia lymphoma (ATLL), angioimmunoblastic T-cell lymphoma (AITL), intravascular large B-cell lymphoma (IV-LBCL), and lymphomatoid granulomatosis (LyG) have the highest incidence of skin involvement. Skin involvement is synchronous with systemic leukemia/lymphoma and often occurs late during the progression of hematological cancer. Exceptions are ATLL, anaplastic large cell lymphoma (ALCL), and follicular lymphoma (FCL) where skin may be the first clinical sign of the systemic disease. Skin infiltration in CLL, lymphoplasmacytic lymphoma/Waldenström’s macroglobulinemia (LPL/WM), and FCL may be a manifestation of large-cell transformation. Clinical manifestations of neoplastic lymphoid skin involvement vary from solitary tumors and nodules to disseminated lesions and erythroderma. Diagnosis relies on skin and peripheral blood phenotyping and clinicopathological correlation. Radiotherapy or surgical excision can be used in addition to systemic therapy.