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Biomimetic Scaffold for Bone Regeneration, Their Manufacturing Techniques and the Applied Materials

  • Monia Trimeche,
  • Ridha Ben Cheikh

摘要

In the realm of clinical practice, bone grafting has evolved to encompass the utilization of various types of grafts, including autogenous, allogeneic, and xenogeneic sources. Additionally, both natural and artificially synthesized materials such as polymers, bioceramics, and composite substances have been integrated into this process. However, these approaches often carry inherent limitations. To address these shortcomings, the concept of biomimetic scaffolds has emerged. These bone implants can assist in accelerating bone regeneration, similar to that of authentic tissue, which replicates the cellular environment within a living organism. This chapter aims to provide a comprehensive overview of the diverse array of biomaterials utilized in these scaffolds, coupled with the methodologies employed in the fabrication of biomimetic scaffolds. Moreover, the discussion delves into the intricacies of the limitations posed by intelligent biomaterials.