Biomedical Applications of Magnetically Functionalized Nanoparticles

Incorporating magnetically functionalized nanoparticles into biomedical contexts have emerged as a revolutionary avenue within nanomedicine. This summary briefly describes about the synthesis, characterization, and various biomedical applications of the functionalized nanoparticles. It discusses synthesis techniques, encompassing both chemical and physical methods, and explores approaches to surface functionalization, with the improved biocompatibility and targeted functionalities. The chapter emphasizes the crucial role of magnetically functionalized nanoparticles in biomedical imaging, particularly in contrast enhancement and multimodal imaging for magnetic resonance imaging (MRI). The exploration extends to apply these nanoparticles in drug delivery systems, focusing on the controlled drug release, targeted delivery, and their use in magnetic hyperthermia for cancer therapy. Moreover, the chapter delves into the realm of theranostics, wherein magnetic nanoparticles play dual roles in both diagnostics and therapeutics, with a specific focus on cancer treatment. The discussion extends to consider toxicological aspects and biocompatibility, drawing insights from in vitro and in vivo studies that address potential immunological responses and long-term toxicity.