Health Digital Twins with Clinical Decision Support and Medical Imaging

As the concept of digital twins as virtual representations of physical entities is rapidly gaining popularity in healthcare, this paper studies the feasibility of incorporating clinical decision support (CDS), clinical data, and medical imaging into health digital twins (HDTs). A HDT is visualized in a web application, health data are stored in a FHIR-based electronic health record, computed tomography images are stored in a rudimentary DICOM-based picture archiving and communication system. An Arden-Syntax-based CDS system consisting of an interpretation and an alert service is connected. The prototype focuses on interoperability of these components. The study confirms the feasibility of CDS integration into HDTs and provides insight into possibilities for further expansion.