Scaling Laws of Coronary Growth and Remodeling

As discussed in Chaps. 3 , 4 , and 5 , growth and remodeling of coronary vasculature are complex processes that occur during both normal physiology (exercise, pregnancy, aging, etc.) and in pathophysiology (hypertension, hypertrophy, heart failure, etc.). Mathematical models can be very useful in describing growth and remodeling of the coronary vasculature for understanding the underlying principles of the biological response to physical or chemical stimuli. The analytical models described in this chapter can also be useful for the diagnosis and treatment of coronary artery disease using percutaneous coronary intervention or coronary artery bypass surgery as described in Chaps. 7 and 9 , respectively.