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Fibonacci’s Blueprint in Lifespan: Integrating Mathematical Predictions with RNA Dynamics and DNA Heritability in Systems Biology

  • Robert G. Sacco,
  • John S. Torday

摘要

Lifespan, characterized by significant interspecies variation, is shaped by an intricate interplay of genetic, environmental, and physiological factors. This study, anchored in systems biology, explores the influence of entropy, fractals, and Fibonacci energy optimization on lifespan evolution. Using the AnAge database, we elucidated the patterns linking the complex mechanics of aging with the Fibonacci sequence. Notably, our findings reveal a significant association between maximum lifespan and Fibonacci age, fostering an intriguing discourse on their connectedness. This connection sparks additional inquiries into the mechanisms and evolutionary significance of Fibonacci energy optimization in lifespan regulation. By weaving RNA structomics and DNA heritability considerations into a systems biology framework, we aim to unravel the sophisticated interactions bridging genotypes and phenotypes, offering fresh insights into the principles governing lifespan variation. Our study, synergizing systems biology principles with empirical examination, provides valuable insights into the multifaceted nature of lifespan and sets the foundation for future investigations in this fascinating field.