The Use of Complementary and Alternative Medicine in Pediatric Neuro-Oncology

Complimentary and alternative medicine (CAM) is increasingly being used in pediatric oncology but is often underestimated by healthcare teams. The widespread availability of information on the internet has contributed to the rise of its use. Despite the growing body of literature on CAMs in general pediatric oncology, limited research has been conducted specifically on its use in pediatric neuro-oncology. This chapter reviews some of the current existing literature on CAMs in pediatric brain tumors, including preclinical and clinical studies which have mainly shown anti-tumoral properties. Additionally, the challenges and ethical concerns posed by alternative medicines are also discussed. While CAM use presents complex issues for healthcare providers, efforts should be made to provide updated and accurate information to families and patients. Prospective trials, particularly in children with brain tumors, investigating its safety, toxicity, and efficacy will remain a challenge for future researchers but is something that should be encouraged.