Pyoderma Gangrenosum

Pyoderma gangrenosum (PG) is a very rare ulcerative neutrophilic inflammatory skin disease. The clinical manifestations of PG are pain, tenderness, an erythematous nodule, or a sterile pustule in the early stage, which progress to deep ulcers with a purulent base and undermined margin. The ulcers heal with characteristic cribriform scars; however, sometimes multiple relapses occur. The patients with PG have frequently an associated systemic disease including inflammatory bowel disease, arthritis, hepatitis, or malignancy.