Livedo(id) Vasculitis

Livedoid vasculitis (LV) is a rare vasculopathic disorder. LV is responsible of recurrent flares of painful purpuric, ulcerative lesions that heal with porcelain white atrophic scars. The mechanism underlying LV is a thrombo-occlusive vasculopathy associated or not with an underlying coagulopathy or disorder of connective tissue diseases. The therapeutic management of LV lacks evidence and specificity. A wide panel of therapies have been used including antiplatelet and anticoagulant agents, fibrinolytics, immunosuppressants, and pain control and compression, but the efficacy remains a matter of controversy. The use of combined therapies to target the different phases of the disease may represent a promising approach in the near future.