A surgical wound complication has considerable impact on the patient’s quality of life and on the wider healthcare setting, and it remains a significant challenge for clinicians as one of the leading causes of morbidity. Proper postoperative management of surgical wounds can reduce the rate of surgical site infections, even though patient-related risk factors, type of surgery and surgical technique are all components of a holistic assessment process. In this context, the surgical team’s goal is to protect surgical incisions from external contamination, remove any obstacles to the healing process while taking into account patient comfort and good cosmetic outcome, and identify early any signs of complications. Many different types of dressings are available, but it is still unclear whether any one type is better than the others. There is a rapidly emerging body of literature on the effect of incisional negative pressure wound therapy on closed clean/clean-contaminated surgical wounds in preventing wound complications (such as infection, dehiscence, seroma, hematoma, and peri-wound maceration).