Students who are deafblind are a highly heterogeneous and rare group in the United States and in the world. All students who are deafblind require specially designed instruction co-created by teachers and other personnel with expertise in deafblindness (DB). In this chapter, the authors explore core, research-supported practices that all educators may use to more effectively teach students who are deafblind. In order to provide better access to instruction, the role of touch as a confirmatory and primary learning sense is discussed as an overarching principle and value for students who are deafblind. Using case studies, nationally recognized teacher competencies, and available research, the authors explore practical approaches for supporting student success through family partnership, well-planned teaching routines, infusion of communication and literacy opportunities, promotion of orientation and mobility skills throughout the day, and direct instruction for learning social skills.