Epigenetic Inheritance

The field of epigenetics, orchestrating molecular communication at the genome-phenotype interface, has gained significant importance over the last decades. Mitotic inheritance, ensuring the propagation of epigenetic information throughout cell division, is crucial for preserving cell fate, functionality, organisms’ development and for transcriptional memory of past events. In addition, the more elusive meiotic inheritance, responsible for transmitting epigenetic information across generations, may contribute to intergenerational or transgenerational disorders or empower offspring with the ability to prosper under specific environmental contexts. This this book chapter provides an in-depth description of the intricate mechanisms governing epigenetic information transmission during both mitosis and meiosis, with illustrative examples. Furthermore, the chapter investigate the role of epigenetic inheritance in environmental studies, addressing current challenges and offering perspectives for future research in this dynamic field.