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RNA-Mediated Inheritance of Mammalian Spermatozoa

  • Minoo Rassoulzadegan,
  • Zeynep Yilmaz Sukranli,
  • Ecmel Mehmetbeyoglu Duman

摘要

RNA and DNA carry memories to transmit information to future generations. If the role of DNA, with its laws of genetics, is that of a recognized and essential transporter for complex organisms, on the other hand the role of RNA is variable and is not yet understood. We list here the experiments in mice which confirm the role of RNA in non-Mendelian transmission by inducing variations in the expression of a gene or a group of genes. These changes occur at the level of transcriptional expression and are accompanied by the expression of new phenotypes, then hereditary over several generations.