Soft tissue and bone tumors can present in many ways and sometimes in a subtle way. It is important for physicians to be aware of this to make a correct diagnosis and suspect these tumors. Sports physicians are challenged by the wide spectrum of pathology that is present in their offices and confounding presentations that can delay the diagnosis of tumors. Correct and timely referral is the key to properly treating these patients. Skeletal pain with no trauma, chronic hematomas, chronic swelling in joints, weight loss, night sweats, and growing masses are some of the subtle symptoms that need the attention of practitioners. Benign and malignant tumors are very rare, but a misdiagnosis can bring devastating consequences.