Cyber-Medical Systems in Chemotherapy Treatment Optimization
摘要
The application of engineering in medical practice has a long history; however, these systems are generally used for diagnosis. The cyber-medical system approach combines engineering and biology to enhance the treatment of patients. For example, artificial pancreas systems have proved that the achievements of modern technology can be successfully applied in treating chronic diseases. The chapter discusses the application of control theory in the treatment of cancer. Therapy optimization comprises the steps of modeling, parameter identification for personalization, and therapy optimization based on control theory and mathematical optimization. The sections of the chapter discuss these problems with the current solutions being used in the Physiological Controls Research Center of Óbuda University.