RadiationRadiation is usedRhodium-based alloys in manyRhodium-platinum alloys areas such as medicalMedical uses, academic and scientific applicationsApplication, industryIndustry, nuclear power plantsNuclear power plants, and its use is increasing in many areas such as agricultureAgriculture, spaceSpace research and defense industryDefense industry with developing technology. The adopted ways to protect from ionizing radiationIonizing radiation are timeTime, distanceDistance, and shieldingShielding. Although radiation protectionRadiation protection is limited with timeTime and distanceDistance, the amount of radiationRadiation exposed can be reduced by shieldingShielding to reliable levels. In cases where the timeTime and distanceDistance are insufficient, the shieldingShielding process must be taken into account. Today, the most preferred material for protectionProtection from ionizing radiationIonizing radiation is leadLead platesPlate or shielding materialsShielding material made from lead derivativesLead derivatives. LeadLead is among the most toxicToxic elements known in nature and no exposure threshold value has been given by the World Health OrganizationWorld Health Organization and it has been recommended to be avoided completely. For this reason, researchers have intensively searched for new materials as an alternative to leadLead . Currently, for this purpose, studies on the determination of ionizing radiation shieldingIonizing radiation shielding properties of glassesGlass, concretesConcrete, compositesComposite, alloysAlloy and ceramicsCeramic are carried out and continue. In the present chapter, nuclear radiation shieldingNuclear radiation shielding characteristics of platinumPlatinum and rhodiumRhodium-based alloysAlloy were investigated. To investigate the gamma radiation attenuationGamma radiation attenuation properties, the massMass and linear attenuation coefficientsLinear attenuation coefficient, half and tenth value layersTenth value layer, mean free pathMean free path values, effectiveEffective mass atomic numbersEffective atomic number, electron densitiesElectron density and conductivityConductivity were determined in the gamma energyEnergy range of 0.060 to 2.614 MeV. TheoreticalTheoretical and simulation codesSimulation code (MCNP6 and GEANT4GEANT4)MCNP6 were used to determine the gamma radiation attenuationGamma radiation attenuation parametersParameter. Then, the interactionsInteraction of charged particlesCharged particle with matter were investigated by determining the proton mass stopping powerProton mass stopping power, proton projected rangeProton projected range, alpha mass stopping powerAlpha mass stopping power, and alpha projected rangeAlpha projected range parametersProjected range parameter. The obtained nuclear radiation shieldingNuclear radiation shielding data are of great importance for the above-mentioned applicationApplication areas and shows that the presented alloysAlloy can be used as alternative shielding materialsShielding material.