Structural and Functional Changes in Skin of the Diabetic Foot
摘要
Dermatologic conditions which are related to diabetes include acanthosis nigricans, characterized by a hyper-pigmented, velvety, cutaneous thickening that appears predominantly in the neck, axilla, and groin areas; necrobiosis lipoidica (NL), a chronic, necrotizing, granulomatous skin disease; granuloma annulare; diabetic bullae and diabetic dermopathy; and infections. As these conditions can be present in the lower extremity, they should be sought and easily recognized by the health care providers who manage the diabetic lower extremity.