The Epidemiology of Diabetic Foot Ulcer and Amputation

Lower extremity amputation (LEA) and foot ulcer (DFU) are important complications of diabetes. Incidence and prevalence are two epidemiologic measures that indicate new events and events that are currently present. The incidence and prevalence of LEA and DFU vary worldwide and also within countries. Of note, the incidence of LEA appeared to be decreasing in the early part of this century but now in many countries is increasing. The increase is often associated with minor amputations. Individuals who have diabetes and DFU or LEA are at increased risk of death. The costs associated with care for individuals with LEA or DFU are higher than for those with diabetes who do not have LEA or DFU.