Drug Delivery Systems for Cartilage
摘要
A dense network of extracellular matrix and lack of vascularization pose a major challenge in the delivery of therapeutics in the cartilage. Recent advances in material science and nanotechnology have shown the potential to overcome these barriers in cartilage. This chapter focuses on the pathophysiology of cartilage and discusses various drug delivery systems applied in cartilage for various cartilage-associated diseases and cartilage tissue regeneration. These drug delivery systems are majorly classified into nanoparticles, microparticles, hydrogels, and transdermal platforms, which follow different routes of entry.