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Do Cancer Cells Collaborate During Metastasis?

  • Fred J. Vermolen,
  • Qiyao Peng,
  • Daphne Weihs

摘要

We consider a model for cell deformation and cellular forces that are exerted on the immediate environment. This model is applied to the transmigration of cancer cells through narrow, deformable channels. This migration process is an important and rate-determining mechanism during the metastasis of cancer.