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Exploring the Impact of Latent and Obscure Factors on Left-Censored Data: Bayesian Approaches and Case Study

  • Pragya Gupta,
  • Arvind Pandey,
  • David D. Hanagal,
  • Shikhar Tyagi

摘要

In the realm of scientific investigation, traditional survival studies have historically focused on mitigating failures over time. However, when both observed and unobserved variables remain enigmatic, adverse consequences can arise. Frailty models offer a promising approach to understanding the effects of these latent factors. In this scholarly work, we hypothesize that frailty has a lasting impact on the reversed hazard rate. Notably, our research highlights the reliability of generalized Lindley frailty models, rooted in the generalized log-logistic type II distribution, as a robust framework for capturing the widespread influence of inherent variability. To estimate the associated parameters, we employ diverse loss functions such as SELF, MQSELF, and PLF within a Bayesian framework, forming the foundation for Markov Chain Monte Carlo methodology. We subsequently utilize Bayesian assessment strategies to assess the effectiveness of our proposed models. To illustrate their superiority, we employ data from renowned Australian twins as a demonstrative case study, establishing the innovative models’ advantages over those relying on inverse Gaussian and gamma frailty distributions. This study delves into the impact of hidden and obscure factors on left-censored data, utilizing Bayesian methodologies, with a specific emphasis on the application of generalized Lindley frailty models. Our findings contribute to a deeper understanding of survival analysis, particularly when dealing with complex and unobservable covariates.