Foot-and-Mouth Disease: A Persistent Challenge for the Livestock Industry
摘要
Foot-and-mouth disease (FMD) is a transboundary highly contagious viral disease of cloven-hoofed animals caused by the FMD virus (FMDV), which belongs to the genus Aphthovirus in the family Picornaviridae. The virus exists as seven distinct serotypes [O, A, C, Asia1, and Southern African Territories (SAT) 1–3] with multiple subtypes in each serotype. The circulation of highly divergent virus serotypes and strains poses a continuing challenge and a major hindrance to international trade in animals and animal products. Owing to the complexity of FMD epidemiology, this chapter uses different epidemiological models (epidemiological triad, chain of infection, natural history of the disease, and infectious cycle) to better understand disease dynamics. This chapter also provides deep insight into disease status, control challenges, and possible prevention practices for FMD.