Botulinum Toxin Therapy-Future Perspectives

New potential applications for botulinum neurotoxin (BoNT) therapy are constantly emerging through the expanding literature in the field of clinical toxicology. In this chapter, we discuss potential indications for botulinum neurotoxin treatment in five major fields of medicine: Psychiatry (depression), cardiology (irregular heartbeats, atrial fibrillation), cancer related disorders (cancer related pain, prevention of post-surgical and post radiation pain, prevention of esophageal narrowing after surgery for esophagal cancer, prevention of parotid gland fistula and cyst formation after parotid cancer surgery and alleviating excessive face sweating and severe jaw pain after first bite following parotid gland surgery). In dermatology, there is evidence that local botulinum toxin injections can help psoriasis and recalcitrant itch as well as palm pain and vascular palm problems associated with Raynaud syndrome. In pain medicine, botulinum toxin injections can help to reduce teeth grinding and associated pain, jaw pain from temporomandibular disorder, pain and discomfort of anal fissure.