Botulinum Toxin Therapy for Autonomic Dysfunction (Excessive Drooling/Sialorrhea and Excessive Sweating (Hyperhidrosis) and for Certain Skin Disorders

Injection of botulinum toxins to the glands reduces the secretion of saliva or sweat by blocking the release of nerve signal transmitter acetylcholine. This action can help patients who suffer from local excessive sweating or those who are affected by persistent drooling. Salivary and sweat glands are located under the skin and are readily accessible to surface injections. The emerging data suggests that intense, recalcitrant local itch and some forms of psoriasis also respond to local botulinum toxin injections.