Bactericidal Activity of Mesoporous SiO2 Matrices Inlaid with Cu° and CuO Nanoparticles Against P. Aeruginosa

The paper presents the results of research into mesoporous SiO2 matrices inlaid with nanoparticles Cu° and CuO to establish the bactericidal activity of powders of the SiO2:Cu° and SiO2:CuO composition against pseudomonas aeruginosa ATCC 27853. The Brunauer–Emmett–Teller method established the dependence of the specific surface of xerogels depending on the concentration of copper oxide and reduced copper. The structure of the resulting xerogels was studied by electron microscopy. It is shown that these xerogels can be used as biologically active substances for applications in creating antimicrobial agents. Reducing particle agglomerates to Cu° in SiO2 matrix can effectively affect the stabilization of antibacterial properties in the system of the xerogel closed pores.