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68Ga-Pentixafor

  • Francesca Russo,
  • Massimo Menichini,
  • Maria Ricci,
  • Laura Travascio,
  • Habibollah Dadgar,
  • Hossein Arabi,
  • Nasim Norouzbeigi,
  • Maria Silvia De Feo,
  • Habib Zaidi,
  • Batool Albalooshi,
  • Andrea Cimini

摘要

In recent years, some new positron emission tomography (PET) radiopharmaceuticals have come to attention as possible alternatives to fluorine-18-fluoro-2-deoxyglucose (18F-FDG) PET. In this context, this chapter describes the role of PET with gallium-68 (68Ga)-Pentixafor, describing potential clinical indications, with interesting clinical cases. Moreover, synthesis, pharmacokinetics and physiological distribution of 68Ga-Pentixafor, and PET acquisition protocols are described as well.